Research films > SHINE trial

SHINE trial – Shorter treatment for minimal TB in children

In 2020 an estimated 1.1 million children fell ill with tuberculosis (TB) globally. A quarter those children are estimated to have died, despite the fact that TB is treatable. This film shows how a ground-breaking multi country randomised controlled clinical trial, co-ordinated by MRC-CTU at UCL and published in the New England Journal of Medicine, has already led to changes in WHO guidelines and will help to fight the spread of TB in children. The full length version includes a discussion about implementing the trial results.

SHINE trial – short version

This shorter version of the film (six and a half minutes in length) provides an overview of the SHINE trial and its findings.

SHINE trial – full version

This full-length version of the film (eleven and a half minutes in length) provides an overview of the SHINE trial and in addition, includes a discussion of how the findings of this research could be implemented in practice.

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